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The National Cancer Mission Hub Bulgaria unites institutions, science, business, municipalities, and civil society organizations in beating cancer efforts

  • It represents a new model of cooperation and exchange of good practices at European, national and regional level
  • 36% of cancer cases are preventable, but prevention starts with education and health culture

The National Cancer Mission Hub Bulgaria (NCMHB) was established at a forum organized by the Bulgarian Joint Cancer Network (BJCN) in partnership with the ECHoS initiative – a pan-European platform uniting over 60 leading organizations from 30+ countries in the fields of healthcare, science, innovation and civic participation. It was held at the GATE Institute of Sofia University “St. Kliment Ohridski” with the participation of a wide range of experts, Bulgarian MEPs, representatives of European cancer organizations and European institutions, and at the end a Memorandum of Synergy and Cooperation was signed to gave a symbolic start to the Hub. The goal is to start a sustainable trans-sectoral partnership between key stakeholders – public institutions, municipalities, academic and professional circles, civil society organizations and business, in sync with the European Mission on Cancer and ECHoS (Establishing Cancer Mission Hubs: Networks and Synergies).

Through NCMHB, this partnership will be structured as a national platform for implementing evidence-based policies in oncology with a focus on early prevention, education, research, digitalization, and social justice.

“We are all working together here to establish the Bulgarian hub on the principle of connectivity and synergy. We are building bridges, creating a sustainable ecosystem by connecting varios experts,” said Assoc. Prof. Dr. Assya Kounsulova, Chair of the Board of Directors of BJCN.

“According to medical data, 36% of cancer cases are preventable, but we need to establish a modern model of prevention based on education. Against the backdrop of all innovations and access to cutting-edge therapies in Bulgaria, we continue to predict cancer mortality of over 60%,” said Ivaylo Petrov, NCMHB coordinator. He presented results of a national survey confirming strong public support and the urgent need to launch a national hub in order to overcome ineffective communication, strengthen intersectoral cooperation with the participation of the state, and integrate into the European cancer control system.

Support for the initiative was expressed by the Ministers of Health Assoc. Prof. Mihail Okoliyski and of Labor and Social Welfare Dr. Hasan Ademov. Dr. Maria Yurukova, Advisor to the President on Social Policies, stated the support of the presidential institution. In a welcoming speech to the forum, Bulgarian Commissioner for Start-ups, Research and Innovation Ekaterina Zaharieva supported the initiative. Andrey Kovachev (GERB/EPP) stressed the need for a Bulgarian hub of the Mission Against Cancer in a welcoming speech. MEP Radan Kanev (DSB/EPP) expressed his readiness to assist through his advisor Zaritsa Dinkova. Prof. Dr. Silviya Ilieva, Director of the GATE Institute, expressed readiness for support and joint work through the opportunities in the field of digital technologies.

“Over the past 10 years,  cancer mortality has been increasing in Bulgaria, while it has been significantly decreasing in the EU. One of the reasons is the lack of health culture at all ages,” said Assoc. Prof. Okoliyski. He expressed the readiness of the Ministry of Healthcare to be an active partner of all organizations in the implementation of the National Anti-Cancer Plan. “Together with you, we want to plan the screening programs, which are long overdue. We are firmly determined that they will start functioning,” the Minister added and announced that the Ministry of Healthcare already has a working group that will take the best from the experience of the National Cancer Registry and integrate it into the National Health Informational System. “I see the NCMHB as one of the key pillars, a coordination unit to share the good practices of the European Cancer Organization. We are ready for an open partnership so that we can have success in a short time,” said Assoc. Prof. Okoliyski.

Psychological support and a clearly outlined patient path are among the most important conditions for a person who has an oncological diagnosis, said Minister Hasan Ademov, MD. He welcomed the creation of the NCMHB as a platform that unites institutions, experts, civil society organizations and which will enable patients to navigate better. Minister Ademov also emphasized that oncological patients must be supported and that they want to be reintegrated into the labor market.

Prof. Galin Tsokov, Director of the Institute of Education, emphasized the need to integrate knowledge from medicine, biology, health education, using much more active teaching methods. This can lead to building skills for preserving and developing students’ health, he said. The transfer of innovations is not at the level and NCMHB can turn into an ecosystem in terms of precisely developing a health culture. Prof. Tsokov reminded of the programs that the Ministry of Education and Science is developing so that skills for a healthy lifestyle are formed from preschool age.

Cancer is one of the most serious challenges for European healthcare systems, with newly diagnosed patients expected to exceed 3.24 million by 2040. Around 40% of cancer cases are preventable and this is a goal that EU countries should work towards together, said MEP Emil Radev (GERB/EPP) in the discussion. Bulgaria has the potential to be an active part of the European system for scientific research and beating cancer efforts, it is important to ensure equal access for Bulgarian patients to new therapies and innovations being developed in Europe. Beating the disease already has a very strong ally – AI to help processing huge volumes of biological data. By the end of the year, eg, access to 60 million cancer images will be provided through the European Cancer Diagnostics Initiative. The genomic data infrastructure is also expected to be operational. We need joint efforts at local, national, European and global levels, the national hubs of the Mission on Cancer can contribute to dialogue and partnership, Radev also said.

The European Beating Cancer Plan and the EU Mission on Cancer are some of the strongest and most concrete examples of European added value – policies that show what Europe can achieve when countries work together on science, prevention, early diagnosis and treatment, said MEP Kristiyan Vigenin (BSP/Progressive Alliance of Socialists and Democrats), who also participated. The National Hubs of the Mission Against Cancer create a bridge between research, policy and the real needs of patients, and it is through such platforms that we can turn European policies into concrete results for each Member State. Investment in health and research are strategic to the future of Europe, and there is very broad party support in the EP on the topic of beating cancer. “Our task will be to protect the funding of key programs such as Horizon Europe, EU for health and the Mission on Cancer in the next European budget. For countries like Bulgaria, European healthcare initiatives are particularly important because they help reduce inequalities in access to innovations and good practices, and therefore it is a strategic priority for us to be part of these platforms,” ​​said Vigenin.

The Bulgarian ecosystem of the Mission on Cancer already includes over 90 organizations and institutions, united by BJCN. Supported by the EC through the Directorate-General for Research and Innovation, BJCN took on the responsibility of building a network for cooperation and dialogue aimed at the introduction and implementation of systemic solutions and policies on health literacy, prevention, early diagnosis, treatment and improved quality of life of patients and their relatives. The creation of the Bulgarian hub was welcomed by representatives of the pilot countries with national hubs Poland, the Netherlands, Greece, Malta, Portugal, who shared their experience in overcoming challenges, achieving goals, and securing funding.

What is the ECHoS project, what is the benefit of the exchange of good practices between the hubs and what are the tools that the Bulgarian hub can benefit from as part of the pan-European network, explained Anabela Isidro, coordinator at ECHoS.

Kay Duggan-Wallace from the Directorate-General for Research and Innovation (DG RTD) spoke about the need to build a bridge between the European Commission and the Member States to share priorities and good practices in the care of cancer patients and to develop common strategies to combat cancer, adequate for each country.

How national hubs cover the path of cancer patients in diagnostics, therapy and overall cancer care, explained Matthias Schuppe from the Directorate-General for Health and Food Safety (DG SANTE).

In an interview for the forum, Prof. Christine Chomien, Vice-President of the EU Council for the Mission on Cancer, noted that the hubs represent an innovative approach at European level that effectively connects science and society, all stakeholders in the fight against cancer.

Alberto Costa, MD, PhD, CEO of the European School of Oncology (ESO), emphasized the paramount importance of the quality of cancer care and the need to work against inequalities in patient access.

About the initiative:

In 2024, BJCN was officially included as the national representative of Bulgaria in the European ECHoS initiative, uniting over 60 leading organizations from 30+ countries. With a mandate until 2031, the initiative aims to establish National Hubs of the Mission on Cancer in all Member States, with Bulgaria being among the first pilot countries.

BJCN is a non-governmental public benefit association that unites over 20 scientific societies and over 5,000 healthcare professionals. The organization works to integrate education, science, innovation and healthcare through evidence-based policies. Its main objectives include promoting partnerships, creating innovations in oncology care and structured participation of Bulgaria in the pan-European process of tackling cancer.

The National Cancer Mission Hubs are a management structure of the European Mission against Cancer, operating at national, regional and local levels in each EU Member State or associated country. By promoting collaboration, dialogue and partnerships between different stakeholders – including policymakers, healthcare professionals, researchers, businesses, patients and citizens – play a key role in joining forces and accelerating research and innovation in the field of cancer prevention, treatment and improving the quality of life of cancer survivors and their families.

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SCIENTIFIC PERIODICALS

Coordinator: Prof. Dr. Alexander Yulianov

Periodicals and book publishing BJCN-MORE

  • MORE Library: Oncological monographs by Bulgarian and foreign authors, dedicated to current problems of prevention, screening, diagnostics, TNM-staging and treatment of malignant diseases in adults and children
  • OncoSofia – official journal of BJCN in open access format

FINANCE, MEDIATION AND ETHICAL CONTROL

Coordinator: Dr. Marchela Koleva

In partnership with the law firm Murgova and partners, BJCN prepares, updates and publishes various documents on legal and ethical norms for a cluster organization.

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PEDIATRIC ONCOHEMATOLOGY

Coordinator: Assoc. Prof. Dr. Boryana Avramova

BJCN finances and publishes for the first time in Bulgaria a licensed translation of the Toronto Guidelines for Staging of Pediatric Malignancies

In collaboration with the Bulgarian Medical Society of Hematology (BMSH), the Bulgarian Medical Society of Pediatric Hematology and Oncology (BMDDHO) and the Bulgarian Society of Pediatric Surgery (BDS) joint events are held under a training program on the topic: Pediatric Oncohematology
June 12, 2021: Morphology of blood cells
June 4, 2022: Diagnosis of acute lymphoblastic leukemia
November 25, 2023: Fundamentals of classification and staging of hematolymphoid and pediatric neoplasias
November 23, 2024: Diagnosis of acute myeloblastic leukemia

DIGITAL SOLUTIONS AND INNOVATIONS

Coordinator: Lybomir Balabanski

Teleoncology
BJCN partners with the Bulgarian company Shemha Health in the development and testing of an innovative teleoncology platform PrOPA (Precision Oncology Patient Advice). The platform functions as a digital tumor board for personalized oncology care, uniting all diagnostic and therapeutic modalities within a single digital, integrated oncology center. ProPA is designed to optimize processes in oncology care by providing precise and evidence-based treatment recommendations, reducing the time for clinical decision-making and facilitating a multidisciplinary approach in the treatment of cancer.

BJCN is in collaboration with the International Agency for Research on Cancer (IARC) on the implementation of the CanScreen-ECIS project, the aim of which is to improve the quality, monitoring and evaluation of cancer screening programs in Europe. The project supports data collection, capacity building and the adoption of evidence-based policies for effective and equitable early cancer detection.

BJCN participates in Work Package 4 (Sustainability) of the EU Project eCAN to strengthen eHealth for cancer patients.

Innovations

BJCN partners with the Bulgarian company Shemha Health in the development and testing of an innovative teleoncology platform PrOPA (Precision Oncology Patient Advice). The platform functions as a digital tumor board for personalized oncology care, uniting all diagnostic and therapeutic modalities within a single digital, integrated oncology center. ProPA is designed to optimize processes in oncology care by providing precise and evidence-based treatment recommendations, reducing clinical decision-making time and facilitating a multidisciplinary approach to cancer treatment.

In 2022 in partnership with BGO Software, the innovation MORE e-Guidelines (MORE e-CME-O) has been developed and implemented – an original digital platform for creating and updating evidence-based oncology clinical guidelines.

Projects

SCIENTIFIC RESEARCH

Coordinator: Acad. Prof. Dr. Draga Toncheva

Scientific Research
In partnership with the IT company Kelvin Health and the MORE-Darzalas Foundation, BJCN participated in organizing and conducting a prospective study TICSSO on the possibilities of thermographic imaging for early detection of breast cancer. The design is a product of collaboration between teams of oncology experts and Kelvin Health JSC.
TICSSO: A prospective observational study to compare the effectiveness of thermal imaging versus conventional breast cancer screening procedures (TICSSO)

CONTINUING MEDICAL EDUCATION IN ONCOLOGY AND HEMATOLOGY

Coordinator: Prof. Dr. Margarita Guenova

Continuing Medical Education in Oncology (BJCN CME-O) is a long-term program of BJCN, launched in 2022. It includes conducting educational events in oncology and oncohematology and publishing digital manuals, textbooks and monographs dedicated to malignant diseases

Training seminars
Videoconference modules for continuing medical education in oncology and hematology, thematically dedicated to the most current diagnostic and therapeutic problems in solid tumors and hematological neoplasias. They include lectures by leading experts from Bulgaria and abroad, training demonstrations and credit tests.

The seminars are organized and implemented with the expert participation of associations, members of the Bulgarian Society of Oncology: Women in Oncology Association, Bulgarian Association of Psycho-Oncology (BAPO), Bulgarian Group of Bronchology and Interventional Pulmonology (BGBIP), Bulgarian Medical Association of Hematology (BMSH), Bulgarian Medical Society of Pediatric Oncology and Hematology (BMDDOH) and Bulgarian Society of Pediatric Surgery (BDSHS).

For the first time in the history of Bulgarian clinical oncology and hematology, the training forums are accredited by the Accreditation Council of Oncology in Europe (ACOE) and the European Board for Accreditation in Hematology (EVAN).

Best of the World Forums
From 2025 BJCN presents licensed reviews of the most prestigious oncology forums in the world

BJCN-MORE Clinical Guidelines

  • Evidence-based guidelines. Created annually by national multidisciplinary expert boards and published in paper format since 2010. They include recommendations for clinical behavior in solid tumors of various localization in adults and children, for predictive biomarkers and for psychosocial support in oncology. The Oxford CEBM method was used for evidence analysis and recommendation formulation, and since 2020 – the GRADE approach.
  • Original educational digital product MORE e-CME-O: In 2022 in partnership with BGO Software, the innovation MORE e-Guidelines (MORE e-SME-O) has been developed and introduced – an original digital platform for creating and updating evidence-based oncology clinical guidelines.

Textbooks
Within the framework of the national oncology conferences BJCN-MORE, annual editions of the BJCN-MORE Textbook are published in printed and electronic versions. The textbooks contain scientific articles thematically dedicated to specific malignant diseases in adults and children and are intended for continuing medical education in oncology and hematology. The texts are in the style of literature reviews and are compiled by experts, authors of sections in evidence-based clinical guidelines.

MORE Library
The MORE Library includes oncology monographs by Bulgarian and foreign authors dedicated to current problems of prevention, screening, diagnosis, TNM-staging and treatment of malignant diseases in adults and children

PSYCHOSOCIAL SUPPORT AND SUPPORTIVE CARE

Coordinator: Ekaterina Vitkova

Since March 2022, BJCN has joined the ECO-ASCO Special Network: Impact of the War in Ukraine in Cancer

The Bulgarian Association of Psycho-Oncology at BJCN in partnership with the National Patient Organization and Junior Achievement Bulgaria developed and implemented in 2022-2023 a project of the UICC Solidarity Fund for Ukraine: Mental health for Ukrainian patients with oncological diseases.

BJCN partners with OECI to participate in a pilot project to develop and validate a unified quality of life assessment system based on assessments and preferences of patients who have survived or are undergoing treatment for oncological diseases:
European Oncology Quality of Life (EUonQoL)

PRIMARY AND SECONDARY PREVENTION

Coordinator: Assoc. Prof. Dr. Milena Encheva

BJCN partners with Ino-Med in an international project: Personalized Cancer Primary Prevention Research through Citizen Participation and Digitally Enabled Social Innovation (4P-CAN)
Personalized Cancer Primary Prevention Research through Citizen Participation and Digitally Enabled Social Innovation (4P-CAN) 

BJCN partners with Ino-Med in an international project: Raising awareness and understanding of the importance of COVID-19 prevention in patients with underlying conditions from Romania, Bulgaria, Moldova, and North Macedonia – AWARE-РreCOV19
The AWARE-precov19: Raising awareness and understanding of the importance of COVID-19 prevention in patients with underlying conditions from Romania, Bulgaria, Moldova, and North Macedonia

BJCN partners with the International Agency for Research on Cancer (IARC) at the WHO in the CanScreen-ECIS project, which aims to improve the quality, monitoring and evaluation of cancer screening programs in Europe. The project supports data collection, capacity building and the adoption of evidence-based policies for effective and equitable early cancer detection.
CanScreen-ECIS

BJCN partners with the National Association of General Practitioners in Bulgaria (NSOPLB) to organize training webinars and a roundtable on the topic: The General Practitioner in the Path of the Oncology Patient.
The General Practitioner in Opportunistic Cancer Screening
The General Practitioner in the Cancer Patient’s Journey

COMPREHENSIVE CANCER CENTERS AND NETWORKING

Coordinator: Assoc. Prof. Dr. Assia Konsoulova

Comprehensive Oncology Centers

Since July 2022, BJCN has been an associate member of the Organization of European Cancer Institutes (OECI) – an international non-governmental organization authorized to accredit comprehensive oncology centers in Europe and the world. The official contact person is Assoc. Prof. Dr. Assia Konsoulova.

    • In the period from November 25 to 27, 2025, the first visit to Bulgaria (Deep Dive) was carried out under the accreditation program of the CCI4EU – WP4 project, related to providing support for the development of maturity in structuring centers for comprehensive oncology care.
      The visit was held at the University Hospital “St. Ivan Rilski”, Sofia and was coordinated on the Bulgarian side by Assoc. Prof. Asya Konsulova.

Network connectivity

Since February 4, 2024, BJCN is a full member and representative of Bulgaria in ALL.Can International – an international network of leading representatives of patient organizations, politicians, healthcare professionals, researchers and industry experts from all over the world. The main mission of ALL.Can International is to identify unmet needs in oncology care and, through research and interaction, to demonstrate best practices. The organization develops systemic solutions and policies to improve oncology care by focusing on what is of greatest importance to patients.

Since June 18, 2024, BJCN has been officially included as the representative of Bulgaria in the ECHoS initiative (Establishing Cancer Mission Hubs: Networks and Synergies). ECHoS is a European project uniting over 60 leading organizations in the field of healthcare, research and innovation, academia and the non-governmental sector from 30 countries. Funded under the Horizon Europe programme, the project aims to support the implementation of the Mission to Fight Cancer activities in all Member States and Associated Countries, with a focus on the establishment and development of National Hubs. As part of ECHoS, the ONS takes responsibility for building a network for cooperation and dialogue aimed at the introduction and implementation of policies related to cancer prevention and treatment. The initiative aims to create sustainable synergies and interactions at national and international level, supporting innovative solutions and good practices in cancer care.

Since 27 November 2024, the ONS has been an associate member of the European Cancer Organisation (ECO) – a European federation uniting organisations involved in the field of oncology at European level. ECO focuses on facilitating cooperation to develop and coordinate policies aimed at improving the quality of care for patients with cancer. This is achieved through interprofessional and multidisciplinary interaction between medical and non-medical organisations, as well as experts from different public sectors.

CLINICAL GUIDELINES, PERIODICALS, CONFERENCES/ASSEMBLIES

Coordinator: Assoc. Prof. Dr. Dimitar Kalev

BJCN-MORE Expert Boards

Since 2010, National Expert Multidisciplinary Boards have been formed, which annually create national guidelines for clinical behavior in a specific localization of cancer. Members of the expert boards (EB) are leading specialists from all areas of Bulgarian clinical oncology and are determined depending on the localization of the oncological disease. The nominal composition of the EB is published in the relevant annual editions of the clinical guidelines and textbooks.

BJCN-MORE Clinical Guidelines

Guidelines based on evidence, created annually by national multidisciplinary expert boards since 2010. They include recommendations for clinical behavior in solid tumors of different localization in adults and children, for predictive biomarkers and for psychosocial support in oncology. The Oxford CEBM method was used to analyze evidence and formulate recommendations, and since 2020, the GRADE approach.

In 2022, the innovation MORE e-Guidelines was introduced – an original digital platform for creating and updating evidence-based oncology clinical guidelines.

Clinical Guidelines BJCN-MORE
MORE e-Guidelines

Annual Assembly BJCN

Annual representative forum of BJCN as a cluster of industry associations, held since 2022. Includes reporting and election meetings, scientific and other joint events dedicated to current problems in the organization and health policies for the provision of oncological care in Bulgaria. Since 2024, it has initiated strategies for international integration and the establishment of a National Hub of the Mission against Cancer in Bulgaria.

Annual Assembly BJCN

Conference MORE

An annual national scientific forum with multidisciplinary participation, held since 2010 with a thematic focus on specific malignant diseases in adults and children. It includes plenary and discussion sessions and presentations of national evidence-based clinical guidelines and textbooks. Since 2022, it has been an official scientific event within the framework of the BJCN Annual Assembly.

Annual Conferences BJCN-MORE 2010-2024
Annual Conference BJCN-MORE 2025

Textbooks BJCN-MORE

Within the framework of the national oncology conferences BJCN-MORE, annual editions of the BJCN-MORE Textbook are published in printed and electronic versions. The textbooks contain scientific articles thematically dedicated to specific malignant diseases in adults and children and are intended for continuing medical education in oncology and hematology. The texts are in the style of literature reviews and are compiled by experts, authors of sections in evidence-based clinical guidelines.

Textbooks